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April 24, 2023Cancer ResearchOpen Access

Angiopoietin-2–Dependent Spatial Vascular Destabilization Promotes T-cell Exclusion and Limits Immunotherapy in Melanoma

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Authors

HPHa-Ram ParkASAnahita ShivaPCPortia Cummings

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Cite This Study

Park et al. (2023) studied this question.

synapsesocial.com/papers/6a87abc4a9eb41bcdfc4db6dhttps://doi.org/10.1158/0008-5472.can-22-2838
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation2016 · 249 citations
  2. 2The Complex Role of Angiopoietin-2 in the Angiopoietin-Tie Signaling Pathway2012 · 267 citations
  3. 3Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy2019 · 90 citations
  4. 4Tumor Cell–Derived Angiopoietin-2 Promotes Metastasis in Melanoma2020 · 48 citations