Why the study?
Understanding the mechanisms and shared risk factors between cardiovascular and oncological diseases is important for improving outcomes, preventing comorbidities, and guiding patient lifestyle modifications.
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Design
Review
Understanding the shared risk factors and inflammatory mechanisms between cardiovascular disease and cancer is crucial for developing common preventive and diagnostic strategies.
Cardiovascular (CVD) and oncological diseases (OD) are the main causes of death worldwide and account for a heavy burden on economy, disability and mortality in many countries. Clear understanding of the mechanisms shared by CVD and cancer is important for increasing the life span and quality of life in cancer survivors as well as for preventing comorbidities and correct instructing the patients about risk factors and lifestyle modifications. Both groups of diseases share risk factors, including smoking, obesity, diabetes mellitus, alcohol consumption, unhealthy diet, etc. Along with these factors, inflammation may play a key role as it promotes both types of diseases and accompanies obesity, diabetes mellitus, arterial hypertension, and dyslipidemia. Better understanding of the interaction between CVD and cancer will allow creating common effective diagnostic and preventive strategies and safe approaches to the treatment.
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Zvolinskaya et al. (2020) studied this question.
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