Nuclear Magnetic Resonance is today one of the best methods available for the conformational analysis of cyclohexane derivatives. It is possible with this technique to investigate the spatial orientation of the substituents in fixed molecules, as well as the equilibrium position in mobile systems. For these determinations the areas under the signals, the chemical shifts, the coupling constants, and the band widths of particular signals can be used.
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Franklin et al. (1965) studied this question.
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