Clinical Significance of Natriuretic Peptides and Cyclic GMP in Hemodialysis Patients with Coronary Artery Disease

50 subjects total: 19 hemodialysis patients with coronary artery disease (mean age 63 +/- 12 years), 20 hemodialysis patients without cardiac disease (mean age 61 +/- 15 years), and 11 healthy volunteers.

Hemodialysis

Pre-hemodialysis vs post-hemodialysis, and comparison across the three groups (CAD, no cardiac disease, healthy volunteers)

Plasma concentrations of ANP, BNP, and cGMP before and after hemodialysis, and their correlation with indices of left ventricular functionsurrogate