Why the study?
Is moderate/severe hypoglycemia associated with impaired heart rate variability in patients with type 1 diabetes mellitus?
Population
Consecutive patients with type 1 diabetes mellitus
Comparison
Moderate/severe hypoglycemia vs Absent/minor hypoglycemia
Design
Cohort
Authors
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May flag higher hypoglycemia risk in T1DM; hypothesis-generating for HRV monitoring and requires prospective validation.
Is moderate/severe hypoglycemia associated with impaired heart rate variability in patients with type 1 diabetes mellitus?
Impaired heart rate variability on spectral analysis is independently associated with moderate/severe hypoglycemia in patients with type 1 diabetes, reflecting decreased parasympathetic tone.
Silva et al. (2016) studied this question.