April 1, 1996Nephrology

Detection of monocyte chemoattractant protein‐1 (MCP‐1) and its receptors in mesangial proliferative glomerulonephritis

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Population

40 patients with mesangial proliferative glomerulonephritis (mesPGN)

Design

Cross-sectional

Authors

FYFumio YamauchiSemmelweis University AKAbul KashemUniversity of Dhaka MEMasayuki EndohThe University of Osaka

Discussion

Member takes

Implication

MCP-1 may mark interstitial injury in mesangial proliferative GN; leaves open its causal role and therapeutic potential.

Structured PICO

Population

40 patients with mesangial proliferative glomerulonephritis (mesPGN)

Outcome

Expression of MCP-1 and its receptors (CKR-1, MCP-1a, MCP-1b) at mRNA levels in renal tissuessurrogate

MCP-1 expression correlates with renal function and interstitial damage in mesangial proliferative glomerulonephritis, suggesting a role in disease progression.

Cite This Study

Yamauchi et al. (1996) studied this question.

synapsesocial.com/papers/6a87c57a1fec1a0b3d262ca8 https://doi.org/10.1111/j.1440-1797.1996.tb00071.x

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Ask AI

Bookmark

Detection of monocyte chemoattractant protein‐1 (MCP‐1) and its receptors in mesangial proliferative glomerulonephritis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Detection of monocyte chemoattractant protein‐1 (MCP‐1) and its receptors in mesangial proliferative glomerulonephritis

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider