This review suggests that nitrous oxide remains a versatile and beneficial agent in anesthesia, with many of its claimed adverse effects being overstated.
Does not warrant avoiding nitrous oxide on outdated concerns; leaves open the need for updated RCTs in contemporary practice.
In the first two parts of this series, the basic science of nitrous oxide (N2O) was reviewed and some of its claimed risks and benefits were analysed. In this, the third and final instalment, the remaining risks and benefits will be assessed and the alternatives to nitrous oxide will be evaluated. It will be shown that many of the claimed adverse effects of nitrous oxide either do not exist or are overstated. Nitrous oxide is a versatile agent with many potential benefits during all phases of anaesthesia.
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K De Vasconcellos (2010) studied this question.
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