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December 1, 2009Croatian Medical JournalOpen Access

Higher Serum Uric Acid on Admission Is Associated with Higher Short-term Mortality and Poorer Long-term Survival After Myocardial Infarction: Retrospective Prognostic Study

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Why the study?

Is higher serum uric acid on admission associated with higher short-term mortality and poorer long-term survival in patients with acute myocardial infarction?

Population

621 consecutive patients with verified acute myocardial infarction admitted within 48 hours of symptom…

Design

Cohort

Follow-up

in-hospital, 30-day, and long-term

Authors

SCSiniša CarVTVladimir Trkulja

Discussion

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Overview

May support risk stratification by admission SUA in AMI; leaves open whether lowering levels improves outcomes.

Structured PICO

Is higher serum uric acid on admission associated with higher short-term mortality and poorer long-term survival in patients with acute myocardial infarction?

P
Population
621 consecutive patients with verified acute myocardial infarction (AMI) admitted within 48 hours of symptom onset, age 27-90 years, 64.7% men, 77.5% AMI with ST elevation.
I
Intervention
Higher serum uric acid (SUA) levels on admission (evaluated per 10 micromol/L increase)
O
Outcome
In-hospital mortality, 30-day mortality, and long-term all-cause mortalityhard clinical

Higher serum uric acid levels on admission in patients with acute myocardial infarction are independently associated with increased short-term and long-term mortality.

Cite This Study

Car et al. (2009) studied this question.

synapsesocial.com/papers/6a87d0368111c1e98f48fc80https://doi.org/10.3325/cmj.2009.50.559
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