Why the study?
Do serum uric acid and cardiac biomarkers on admission predict short-term in-hospital mortality in critically ill patients with NSTEMI?
Do serum uric acid and cardiac biomarkers on admission predict short-term in-hospital mortality in critically ill patients with NSTEMI?
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Admission levels of serum uric acid, combined with CK-MB and Troponin-I, may help predict short-term in-hospital mortality in critically ill NSTEMI patients.
1 Abstract Cardiovascular disease (CVD) is the leading cause of death worldwide. Several epidemiological studies have proved that serum uric acid (SUA) is associated with CVD. It is unclear whether increased levels of SUA in CVD promotes or protects against cardiovascular damage. In the present study, we sought to investigate whether the levels of SUA and cardiac biomarkers (Creatine kinase (CK)-MB and Troponin-I) determined on admission will serve as predictors of mortality in non-ST Elevation Myocardial Infarction (NSTEMI) patients during short term in-hospital stay. The results revealed that the mean levels of SUA in males were significantly higher (P 5 mg/dl (females) as compared to control subjects or those discharged. In conclusion, determination of circulating CK-MB and TPN-I levels on admission adds prognostic indicator value to SUA in early prediction of mortality in NSTEMI patients.
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Reddy et al. (2015) studied this question.
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