Evolving Clinically Useful Predictors of Recovery from Intravenous Anesthetics

Thomas W. Schnider, M.D., Research Fellow, Stanford University, Stanford, California, Staff Anesthesiologist, Kantonsspital, Luzern, Switzerland.Steven L. Shafer, M.D., Staff Anesthesiologist, Palo Alto VA Health Care System, Palo Alto, California, Associate Professor of Anesthesiology, Stanford University, Stanford, California, Anesthesiology Service (112A), Palo Alto VA Medical Center, 3801 Miranda Avenue, Palo Alto, California 94304.Dr. Schnider is supported by the Swiss National Science Foundation.Accepted for publication August 20, 1995.The complex pharmacokinetics and pharmacodynamics of intravenous anesthetics precludes easily predicting the duration of anesthetic effect after drug administration, which we will subsequently call