Why the study?
Does multichannel magnetocardiography combined with 3D current density reconstruction accurately localize a ventricular tachycardia focus compared to electrophysiological examination?
Does multichannel magnetocardiography combined with 3D current density reconstruction accurately localize a ventricular tachycardia focus compared to electrophysiological examination?
Multichannel magnetocardiography combined with 3D current density reconstruction can accurately localize a malignant ventricular tachycardia focus within 10 mm of the electrophysiological gold standard.
The objective of this case report is to determine the accurate localization of a malignant ventricular tachycardia (VT) focus by combining multichannel magnetocardiographic (MCG) information with morphologic data. The localization was obtained by calculating the three-dimensional current density distribution (3D-CDD) on the left ventricular surface. To estimate the accuracy of this localization technique, examinations of a healthy volunteer were additionally performed. The MCG-signals were recorded in a magnetically shielded room by a 49-channel magnetogradiometer. The corresponding morphologic information was recorded by magnetic resonance tomography (MRT). The coordinate systems were matched with the help of markers. The 3D-CDD was calculated by the Philips CURRY software package. The origin of a malignant VT determined by X-ray images of the ablation catheter position during the electrophysiological examination (EPE), was used as the gold standard. This was then compared with the localization results obtained by the 3D-CDD. It was found that the localization coordinates showed a difference of less than 10 mm.
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A 1999 study studied this question.
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