Population
Single, differentiated cells of mouse neuroblastoma clone N1E-115
Comparison
Addition of 10 mM tetraethylammonium and… vs Normal medium containing 10 mM calcium
Design
Preclinical
Authors
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No clinical translation from neuroblastoma model; leaves open whether regional calcium channel density shapes excitability in mammalian neurons.
Demonstrates a distinct topographical organization of voltage-gated calcium channels in cultured mouse neuroblastoma cells, with higher densities in the soma and growth cone compared to the neurite.
SR Bolsover (1986) studied this question.
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