Population
Platelet-rich plasma (PRP) from different human individuals
Comparison
Thromboxane synthetase inhibitor UK 34787 vs Absence of UK 34787
Design
Preclinical
Authors
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Suggests heterogeneous platelet responses to thromboxane inhibition; leaves open clinical translation from animal models.
The thromboxane synthetase inhibitor UK 34787 shows variable efficacy in preventing sodium arachidonate-induced platelet release across different individuals.
Heptinstall et al. (1983) studied this question.
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