Menopausal Hormone Therapy—Transdermal or Oral

women experience a range of menopausal symptoms, and MHT is a widely adopted treatment option designed to alleviate those symptoms.Menopausal symptoms can drastically affect a woman's quality of life, and such symptoms may include excessive night sweats, insomnia, vasomotor flashes, palpitations, fatigue, irritability, anxiety, depression, and dryness of the genital area. 1,2As many as 75% of menopausal women experience one or more of these symptoms. 1,2They are a direct consequence of decreased estrogen levels.Therefore, estrogen treatment is logical; due to its effectiveness, it is the treatment of choice.Hormone treatment also improves mood, increases satisfaction, and improves quality of life. 2 MHT usually consists of estrogen and/or progestin replacement therapy.HT plays a crucial role in preventing long-term health complications that IntroductIonMenopausal transition is a physical process in women, marking the time of a reduction in overall ovarian function.This biological transition is accompanied by the cessation of menstrual periods.While some women go through menopausal transition with little to no symptoms, a considerable number may encounter numerous challenges and discomforts.These can include common symptoms such as hot flashes, which are sudden feelings of warmth, and specific issues concerning the genital tract, such as dryness in the vulvar and vaginal areas, which may lead to painful intercourse and urinary difficulties.There are even more serious complications of estrogen deficiency, such as osteoporosis and cardiovascular disease.Healthcare providers must be wellinformed when advising patients who go through menopausal transition.They need to understand both the advantages and disadvantages associated with menopausal hormonal therapy (MHT), as well as have knowledge of both hormonal and nonhormonal treatment.Additionally, healthcare professionals must be familiar with the various methods of delivering these treatments to provide the best care personalized to individual women's needs. Menopausal transItIon a n d HorMone tHerapy (HT )Menstrual irregularity is the sole marker that can objectively identify and define the menopausal transition.Patients will perceive this irregularity as skipped menstrual periods or longer durations between periods.There is no one-sizefits-all pattern; each woman will notice a change that is uniquely her own.