Aggressive soft tissue angiomyxoma in the pelvic region (AAM — Aggressive angiomyxoma) is an extremely rare neoplasm that develops mainly in women of reproductive age. AAM can occur at any age with a characteristic solid infiltrative growth type. AAM is described as benign neoplasms with intermediate malignant potential, since the development of local recurrence is possible. In three cases, distant metastasis of AAM has been described. Radical surgery is the main method of treatment. Hormone therapy is used before surgery with a high risk of performing highly traumatic intervention, after non-radical surgical treatment of AAM, the risk of relapse, inoperable AAM.
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Budurova et al. (2025) studied this question.
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