Why the study?
Does pravastatin improve intima-media thickness of the common carotid artery and aortic stiffness in dyslipidemic HIV-infected patients receiving antiretroviral therapy?
Does pravastatin improve intima-media thickness of the common carotid artery and aortic stiffness in dyslipidemic HIV-infected patients receiving antiretroviral therapy?
In dyslipidemic HIV-infected patients on antiretroviral therapy, pravastatin treatment did not significantly improve carotid intima-media thickness or aortic stiffness.
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Pravastatin shows no vascular benefit in dyslipidemic HIV on ART; leaves open whether statins affect arterial structure, pending RCTs.
Boccara et al. (2006) studied this question.
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