Why the study?
Does central pulse pressure correlate better with ascending aorta diameter than brachial pulse pressure in patients with Marfan syndrome?
Population
40 subjects total: 20 patients with confirmed Marfan syndrome and 20 age- and sex-matched control subjects.
Comparison
Measurement of central pulse pressure and… vs Measurement of brachial pulse pressure; healthy…
Design
Cross-sectional
Authors
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Central pulse pressure may better inform aortic monitoring in Marfan syndrome; hypothesis-generating for prospective central hemodynamics studies.
Does central pulse pressure correlate better with ascending aorta diameter than brachial pulse pressure in patients with Marfan syndrome?
Central pulse pressure, rather than brachial pulse pressure, is a major determinant of ascending aorta dilation in patients with Marfan syndrome.
Jondeau et al. (1999) studied this question.
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