Cystic fibrosis transmembrane conductance regulator dysfunction and its treatment

Cystic fibrosis is a genetic condition caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR). Loss or altered function of the product of this gene, the CFTR protein, affects the transport of ions across cell membranes in several tissues in the body which in turn, through mechanisms which are still not fully understood, results in the disease.