Why the study?
Does a reduced dose of prasugrel (5 mg daily) safely prevent stent thrombosis in patients undergoing pipeline embolisation with inadequate response to clopidogrel?
Population
2 patients undergoing elective pipeline embolisation for cerebral aneurysms who were found to have…
Design
Case_series
Follow-up
6 months
Authors
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Should not yet change neurointerventional antiplatelet practice; hypothesis-generating for reduced prasugrel in clopidogrel nonresponders.
Does a reduced dose of prasugrel (5 mg daily) safely prevent stent thrombosis in patients undergoing pipeline embolisation with inadequate response to clopidogrel?
A reduced maintenance dose of prasugrel (5 mg daily) may be a viable alternative for preventing stent thrombosis in neurointerventional patients with inadequate response to clopidogrel.
Jones et al. (2012) studied this question.
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