March 1, 1987Journal of Biological ChemistryOpen Access

recA protein-promoted ATP hydrolysis occurs throughout recA nucleoprotein filaments.

View Full Paper

Ask AI

Bookmark

Population

recA protein and single-stranded DNA cofactors of lengths varying from 16 bases to over 12,000 bases

Design

Preclinical

Authors

SBStephen L. BrennerIndependent Colleges and Universities of Florida RMR. S. MitchellCommonwealth Scientific and Industrial Research Organisation SMScott W. MorricalUniversity of Vermont

Discussion

Member takes

Implication

No immediate clinical implications; leaves open RecA filament models for bacterial recombination studies.

Structured PICO

Population

recA protein and single-stranded DNA cofactors of lengths varying from 16 bases to over 12,000 bases

Intervention

ATP hydrolysis during recA protein-promoted branch migration and cooperative binding

Outcome

Location and rate of ATP hydrolysis (kcat and apparent dissociation constant)

Demonstrates that recA protein hydrolyzes ATP throughout its nucleoprotein filament rather than just at the ends, providing insight into DNA strand exchange mechanisms.

Cite This Study

Brenner et al. (1987) studied this question.

synapsesocial.com/papers/6a87e85291c33485a1fe867d https://doi.org/10.1016/s0021-9258(18)61304-3

View Full Paper

Ask AI

Bookmark

recA protein-promoted ATP hydrolysis occurs throughout recA nucleoprotein filaments.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

recA protein-promoted ATP hydrolysis occurs throughout recA nucleoprotein filaments.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider