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A patient with acute trichinosis was studied to determine the time course of development of elevated IgE levels after ingesting pork infected with Trichinella spiralis. The patient's serum IgE concentration was normal on the 21st day after ingestion. A threefold rise in IgE concentration occurred between the 22nd and 27th days. Elevation of IgE was a late component of the humoral immune response to T. spiralis infection. Trichinosis is the fourth parasitic disease to be associated with elevated IgE levels and the first in which the time course of the IgE rise has been documented.
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Eugene Rosenberg (1971) studied this question.
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