Autonomously proliferating K/D‐restricted cytolytic T cell clones

K/D‐restricted male‐specific cytolytic T lymphocytes (CTL) have been cloned and assayed for male‐specific proliferation in the absence of exogenous interleukin 2 (T cell growth factor). The majority of freshly cloned CTL proliferate in response to cell‐bound antigen. The clones lose their proliferative potential after growing for three weeks in media containing IL2.