Why the study?
Does alimentary lipemia reduce coronary blood flow and myocardial oxygen consumption, and does heparin-induced lipolysis restore them in normal human subjects?
Population
7 normal human subjects fed cream to induce lipemia, 15 fasting controls comparable in age and sex, and 6…
Comparison
Alimentary lipemia followed by administration of… vs Fasting state and pre-heparin lipemic state
Design
Other
Follow-up
45 minutes post-heparin
Authors
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Alimentary lipemia may impair myocardial perfusion in normals; leaves open relevance to CAD and need for targeted trials.
Does alimentary lipemia reduce coronary blood flow and myocardial oxygen consumption, and does heparin-induced lipolysis restore them in normal human subjects?
Alimentary lipemia significantly reduces coronary blood flow and myocardial oxygen consumption, which can be restored to normal by heparin-induced lipolysis.
Regan et al. (1961) studied this question.
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