Association between Cardio-Cerebro Vascular Disease and Depression and Factors Influencing Depression: The Korean National Health and Nutrition Examination Survey in 2014, 2016

Purpose: In this study investigated the association between cardio-cerebro vascular disease and depression was examined and factors influencing depression in adults with cardio-cerebro vascular disease were identified. The Korean National Health and Nutrition Examination Survey (KNHANES) data (2014, 2016), which is representative of the Korean population was used.Methods: Data on 9,651 people (male 4,148, female 5,503; age≥19 years old from the KNHANES (Ⅵ-2, Ⅷ-1) were analyzed using frequency, percentage, x² test, and logistic regression analysis. Depression is defined as major depression with doctor diagnosis or Patient Health Questionnaire-9 score ≥10. Ischemic heart disease (IHD)(myocardial infarction or angina) and stroke were defined as a doctor diagnosis.Results: The prevalence of depression was 20.4% in the IHD group and 22.9% in stroke group, which were statistically significant. After adjusting by sociodemographic, health-related, and independent variables in a logistic regression analysis, IHD (OR=1.91, 95% CI 1.36~2.69) and stroke (OR=1.83, 95% CI 1.23~2.72) were associated with depression. In addition, IHD was significantly associated with depression in women, people divorced or separated, current smokers, people with perceived stress, and hypercholesterolemia. In addition, stroke was significantly associated with depression in women, under the age of 65, with perceived stress.Conclusion: The results of this study show that cardio-cerebro vascular disease is associated with the depression and influencing factors on depression were socio-demographic and health-related characteristics. Therefore, intensive management of depression risk factors and development and application of a program reducing depression for patients with cardio-cerebro vascular disease should be developed.