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December 1, 1998Antimicrobial Agents and Chemotherapy

Characterization of Human Influenza Virus Variants Selected In Vitro in the Presence of the Neuraminidase Inhibitor GS 4071

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Authors

CTChun Y. TaiGilead Sciences (United States)PEPaul A. EscarpeAustralian National UniversityRSRobert W. SidwellSouthern Research Institute

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Tai et al. (1998) studied this question.

synapsesocial.com/papers/6a87f48b4a20e1705414b356https://doi.org/10.1128/aac.42.12.3234
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mutations in a Conserved Residue in the Influenza Virus Neuraminidase Active Site Decreases Sensitivity to Neu5Ac2en-Derived Inhibitors1998 · 185 citations
  2. 2Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity1997 · 1,103 citations
  3. 3Pandemic Influenza‐Confronting a Reemergent Threat1997 · 26 citations