Fluorescence-Based Methods for Detecting Caries Lesions: Systematic Review, Meta-Analysis and Sources of Heterogeneity

Thaís Gimenez; Mariana Minatel Braga; Daniela Prócida Raggio; Chris Deery; David N. J. Ricketts; Fausto Medeiros Mendes

doi:10.1371/journal.pone.0060421

April 4, 2013PLoS ONEOpen Access

Fluorescence-Based Methods for Detecting Caries Lesions: Systematic Review, Meta-Analysis and Sources of Heterogeneity

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Key Points

To comprehensively evaluate the diagnostic accuracy of fluorescence-based methods for detecting caries lesions across various dental surfaces, dentition types, and examination settings.
Systematically searched PubMed, Embase, Scopus, and grey literature through June 2012 for laboratory and clinical studies evaluating fluorescence-based caries detection against a validated reference standard.
Extracted 2×2 diagnostic tables from eligible studies to calculate pooled sensitivity, specificity, Diagnostic Odds Ratios (DOR), and Summary Receiver-Operating Characteristic (SROC) curves while assessing study quality and heterogeneity.
Identified 75 eligible studies from 434 records, showing that fluorescence devices exhibit comparable diagnostic accuracy across primary and permanent teeth, diverse dental surfaces, and both clinical and laboratory settings.
Demonstrated superior diagnostic performance for advanced caries lesions compared to early enamel lesions, alongside moderate-to-high heterogeneity and evidence of publication bias across the literature.

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Implication

Systematic review and meta-analysis finds fluorescence methods detect advanced caries lesions more accurately across human teeth, highlighting their primary diagnostic benefit for deeper decay.

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Gimenez et al. (2013) studied this question.

synapsesocial.com/papers/6a87fc122053543484aa65cf https://doi.org/10.1371/journal.pone.0060421

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Fluorescence-Based Methods for Detecting Caries Lesions: Systematic Review, Meta-Analysis and Sources of Heterogeneity

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Fluorescence-Based Methods for Detecting Caries Lesions: Systematic Review, Meta-Analysis and Sources of Heterogeneity

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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