What question did this study set out to answer?

To describe the clinical manifestations, laboratory features, and natural history of a delayed febrile pleuropericardial complication occurring after myocardial infarction.

April 21, 1956JAMA

A Post-Myocardial-Infarction Syndrome

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Population

10 patients with myocardial infarction followed by a febrile complication resembling idiopathic pericarditis…

Design

Case_series

Follow-up

weeks or months

Authors

WDWilliam W. DresslerUniversity of Alabama at Birmingham

Discussion

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Implication

Recognizes a self-limited post-MI syndrome; leaves open its incidence and management in the reperfusion era.

Key Points

To describe the clinical manifestations, laboratory features, and natural history of a delayed febrile pleuropericardial complication occurring after myocardial infarction.
Clinical evaluation of 10 consecutive cases presenting with a febrile illness resembling idiopathic pericarditis following acute myocardial infarction.
Assessment of physical findings, chest roentgenograms, temperature profiles, and complete blood counts throughout the disease course.
Pericardial friction rubs were detected in 8 of 10 patients, with roentgenologic evidence of pericardial effusion in 2 and pleural effusion in 7.
Marked leukocytosis occurred in 7 of 10 cases, with leukocyte counts reaching up to 35,000 cells/mm³ alongside protracted low-grade fevers punctuated by high fever spikes and acute pain.
Although frequent clinical relapses prolonged the febrile course over weeks or months, all 10 patients ultimately achieved a favorable recovery.

Structured PICO

Population

10 patients with myocardial infarction followed by a febrile complication resembling idiopathic pericarditis with pleuritis and/or pneumonitis

Outcome

Clinical features and course of the post-myocardial-infarction syndrome

This early case series describes the clinical features of a post-myocardial-infarction syndrome (now known as Dressler syndrome).

Cite This Study

William W. Dressler (1956) studied this question.

synapsesocial.com/papers/6a87fc882c11edba2ecf0480 https://doi.org/10.1001/jama.1956.02960510005002

Topics

Pericardial disease

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A Post-Myocardial-Infarction Syndrome

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

A Post-Myocardial-Infarction Syndrome

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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