Cirrhosis of the Liver; An Analysis of 71 Cases

Article1 August 1944CIRRHOSIS OF THE LIVER; AN ANALYSIS OF 71 CASESI. DONALD FAGIN, M.D., FRANK M. THOMPSON, M.D.I. DONALD FAGIN, M.D.Search for more papers by this author, FRANK M. THOMPSON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-21-2-285 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis study represents an analysis of 71 patients with portal cirrhosis observed at the U. S. Marine Hospital, Detroit from 1926 to the present, with particular reference to clinical manifestations. An excellent comprehensive review of the natural history of Laennec's cirrhosis of the liver has been published recently by Ratnoff and Patek,1 who included a bibliography of the recent literature. In order to avoid duplication, we shall limit our comments primarily to statistical analysis of the case material, with but brief amplification upon theoretical considerations.MATERIALThe 71 cases analysed consist of 21 cases wherein the diagnosis of portal cirrhosis...Bibliography1. RATNOFFPATEK ODAJ: The natural history of Laennec's cirrhosis of the liver—an analysis of 386 cases, Medicine, 1942, xxi, 207-268. CrossrefGoogle Scholar2. FLEMINGSNELL RGAM: Portal cirrhosis with ascites—an analysis of 200 cases with special reference to prognosis and treatment, Am. Jr. Digest. Dis., 1942, ix, 115-120. CrossrefGoogle Scholar3. JOLLIFFEJELLINEK NEM: Vitamin deficiencies and liver cirrhosis in alcoholism. Part VII—Cirrhosis of the liver, Quart. Jr. Studies on Alcohol, 1941, ii, 544-583. CrossrefGoogle Scholar4. CONNOR CL: Fatty infiltration of the liver and the development of cirrhosis in diabetes and chronic alcoholism, Am. Jr. Path., 1938, xiv, 347-364. Google Scholar5. CONNOR CL: The etiology and pathogenesis of alcoholic cirrhosis of the liver, Jr. Am. Med. Assoc., 1939, cxii, 387-390. CrossrefGoogle Scholar6. FRAME EG: Lipotropic substances, Yale Jr. Biol. and Med., 1942, xiv, 229-255. Google Scholar7. SCHUMACHER GA: Causative factors in the production of Laennec's cirrhosis with special reference to syphilis, Am. Jr. Med. Sci., 1937, cxciv, 693-700. CrossrefGoogle Scholar8. BALDRIDGE CW: The relationship between antisyphilitic treatment and toxic cirrhosis, Am. Jr. Med. Sci., 1934, clxxxviii, 685-690. Google Scholar9. KATZINWALTERBLUMGART HMJVHL: "Cardiac cirrhosis" of the liver—a clinical and pathologic study, Arch. Int. Med., 1939, lxiv, 457-470. CrossrefGoogle Scholar10. BLOOMFIELD AL: The natural history of chronic hepatitis (cirrhosis of the liver), Am. Jr. Med. Sci., 1938, cxcv, 429-444. CrossrefGoogle Scholar11. MOON VH: Histogenesis of atrophic cirrhosis, Arch. Path., 1932, xiii, 691-706. Google Scholar12. SHAFFER JM: Diseases of the liver in hyperthyroidism, Arch. Path., 1940, xxix, 20-30. Google Scholar13. GLASSEDMONDSONSOLL SJHASN: Sex hormone changes associated with liver disease, Endocrinology, 1940, xxvii, 749-752. CrossrefGoogle Scholar14. MCINDOE AH: Vascular lesions of portal cirrhosis, Arch. Path., 1928, v, 23-42. Google Scholar15. BUTTSNELLKEYS HRAMA: Plasma protein in hepatic disease, Arch. Int. Med., 1939, lxiii, 143-155. CrossrefGoogle Scholar16. MYERSKEEFER WKCS: Relation of plasma proteins to ascites and edema in cirrhosis of the liver, Arch. Int. Med., 1935, lv, 349-359. CrossrefGoogle Scholar17. POSTPATEK JAJ: Serum proteins in cirrhosis of the liver, Arch. Int. Med., 1942, lxix, 67-82. CrossrefGoogle Scholar18. ISRAELREINHOLD HLJG: Detection of cirrhosis and other diseases of the liver by laboratory tests, Jr. Lab. and Clin. Med., 1938, xxiii, 588-596. Google Scholar19. FOLEYKEETANKENDRICKDARLING EFRWABD: Alterations in serum protein as an index of hepatic failure, Arch. Int. Med., 1937, lx, 64-76. CrossrefGoogle Scholar20. FAGINSAHYUNPAGEL IDMRW: Cirrhosis of the liver—the lipotropic action of parenterally administered amino acids, Jr. Lab. and Clin. Med., 1943, xxviii, 987-993. Google Scholar21. SNELL AM: The effects of chronic disease of the liver on the composition and physicochemical properties of blood: changes in the serum proteins; reduction in oxygen saturation of the arterial blood, ANN. INT. MED., 1935, ix, 690-711. Google Scholar22. DARLING RC: Arterial oxygen saturation in cirrhosis of the liver, ANN. INT. MED., 1940, xiv, 898-902. Google Scholar23. CHRISTIAN HA: Bloody pleural fluid, an unusual complication of cirrhosis of the liver, Trans. Assoc. Am. Phys., 1937, lii, 167-170. Google Scholar24. PATEKPOSTVICTOR AJJJC: Vascular "spider" associated with cirrhosis of the liver, Am. Jr. Med. Sci., 1940, cc, 341-347. CrossrefGoogle Scholar25. MALLORY TB: Discussion—case records of the Massachusetts General Hosp., Case No. 26441, New England Jr. Med., 1940, ccxxiii, 731-734. Google Scholar26. SMIRK FH: Capillary permeability in cirrhosis with hypoproteinemia, Clin. Sci., 1935, ii, 57-66. Google Scholar27. SNELL AM: Changing conceptions of portal cirrhosis, Pennsylvania Med. Jr., 1942, xiv, 337-344. Google Scholar28. MALLORY TB: Discussion, case records of the Massachusetts General Hospital, Case No. 26152, New England Jr. Med., 1940, ccxxii, 643-646. Google Scholar29. OBERST FW: Relationship of the chemical structure of morphine derivatives to their urinary excretion in free and bound forms, Jr. Pharmacol. and Exper. Therap., 1941, lxxiii, 401-404. Google Scholar30. OBERST FW: Studies on the fate of morphine, Jr. Pharmacol. and Exper. Therap., 1942, lxxiv, 37-41. Google Scholar31. MEYERPOPPERSTEIGMANN KAHF: Significance of rise of non-protein nitrogen in medical and surgical jaundice, Jr. Am. Med. Assoc., 1941, cxvii, 847-850. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Detroit, Michigan*Received for publication May 24, 1943.From the Medical Service of the U. S. Marine Hospital, Detroit, Michigan. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byChronic Liver Disease and AcetaminophenG. KENNETH JOHNSON, M.D., KEITH G. TOLMAN, M.D., F.A.C.P.CIRRHOSIS IN THE ALCOHOLIC AND ITS RELATION TO THE VOLUME OF ALCOHOL ABUSELiver Disease and Drug TherapyHepatic Encephalopathy: Current StatusCirrhosis of the liver in Iran a prospective study on 66 casesCase 34-1966Unusual Fatal Infectious Complications of Steroid-Treated Liver DiseaseFollow-up Studies on an Unselected Ten-year Material of 360 Patients with Liver Cirrhosis in one CommunityMorphine tolerance in hepatic cirrhosisTHE ELECTROENCEPHALOGRAPHIC DIAGNOSIS OF MANIFEST AND LATENT `DELIRIUM' WITH PARTICULAR REFERENCE TO THAT COMPLICATING HEPATIC CIRRHOSISVarices Oesophagi: A Study of Autopsy MaterialCorrelation of hernia with portal cirrhosisHerniorrhaphy in Cirrhosis of the Liver with AscitesAN ANALYSIS OF 200 ADMISSIONS FOR MASSIVE UPPER GASTROINTESTINAL BLEEDING*S. L. ZIMMERMAN, M.D., F.A.C.P., EDWARD F. ENGEL, M.D., BERNARD LAPIDUS, M.D., EDWARD A. BRADLEY, M.D., HUBERT CLAYTOR, M.D.�ber prim�r multiple Hautcarcinome bei gleichzeitiger terti�rer LuesHazards in the Therapeutic Use of MorphineHepatic Coma 1 August 1944Volume 21, Issue 2Page: 285-297KeywordsArmed forcesCirrhosisLiverMedical services ePublished: 1 December 2008 Issue Published: 1 August 1944 PDF downloadLoading ...