Why the study?
To determine the frequency of aspirin resistance and identify risk factors for its development in patients with coronary heart disease.
What is the prevalence of and risk factors for aspirin resistance in patients with stable coronary artery disease taking 75 mg/day?
What is the prevalence of and risk factors for aspirin resistance in patients with stable coronary artery disease taking 75 mg/day?
Aspirin resistance is present in nearly one-fifth of patients with stable coronary artery disease on standard 75 mg/day dosing, and is strongly associated with older age, female sex, and metabolic comorbidities like diabetes and obesity.
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May identify higher-risk subgroups for testing; hypothesis-generating without prospective outcome data in stable CAD.
Khodjanova SH (2020) studied this question.
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