Why the study?
Does weight-based heparin dosing improve the achievement of therapeutic aPTT compared to standard dosing in patients with unstable angina?
Does weight-based heparin dosing improve the achievement of therapeutic aPTT compared to standard dosing in patients with unstable angina?
Weight-based heparin dosing in unstable angina achieves therapeutic anticoagulation faster and more reliably than standard fixed dosing, though it increases the risk of supertherapeutic levels.
No takes yet. Share an insight, caveat, or question.
Weight-based heparin may achieve therapeutic aPTT faster in unstable angina; hypothesis-generating and should not yet change practice pending RCTs.
Folstad et al. (2001) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: