Baseline cardiac troponin I concentrations in normal Thoroughbred horses in training are < 0.15 microg/L, providing a reference for identifying active myocardial disease.
Provides cTnI reference in healthy Thoroughbreds; leaves open validation for detecting myocardial disease in clinical cohorts.
Cardiac troponin I is a potentially useful test to identify cardiac muscle damage in the horse. Measurements of cardiac troponin I from serum or heparinised plasma samples from 23 clinically normal Thoroughbred horses in race training were analysed through a standard Australian commercial laboratory using the ADVIA Centaur Assay. The cardiac troponin I concentrations were < 0.15 microg/L from all samples. The test was then validated using macerated equine myocardium. Cardiac troponin I concentration may be useful in determining whether poor performance in Thoroughbred horses is related to active myocardial disease.
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Begg et al. (2006) studied this question.
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