Why the study?
Does epidural morphine improve postoperative respiratory function compared to intramuscular morphine in children undergoing urological and abdominal surgery?
Does epidural morphine improve postoperative respiratory function compared to intramuscular morphine in children undergoing urological and abdominal surgery?
Epidural morphine provides better analgesia than intramuscular morphine but does not improve postoperative respiratory function recovery in children after abdominal surgery.
Epidural morphine does not enhance postoperative respiratory function over intramuscular morphine in children; confirms analgesia quality alone does not improve spirometry.
Thirty children undergoing urological and abdominal surgery were entered into a randomised trial comparing the effects of epidural and intramuscular morphine on postoperative respiratory function. The forced vital capacity and the forced expired volume in 1 s were measured before and 6 h after surgery and on each of the following seven days. Significant decreases (p < 0.01) in forced vital capacity and forced expired volume in 1 s were seen after surgery. After the first postoperative day, a gradual recovery in pulmonary function was observed but the measured parameters had not returned to their pre-operative control values by the end of the study. There were no statistically significant differences between the two groups during the study with respect to forced vital capacity and forced expired volume in 1 s. The quality of analgesia was better in the epidural morphine group than in the intramuscular morphine group. The incomplete recovery of pulmonary function suggests that pain is not the only cause of postoperative respiratory changes in these patients.
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Chabás et al. (1998) studied this question.
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