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Wounds that are slow to heal are poorly understood. Clinicians and researchers have attempted to predict treatment outcomes from simple physical measurements without, as yet, understanding the pathogenesis or the role of complications on chronic wounds. Laboratory studies on tissues from biopsies and wound fluids are essential. These must be associated with carefully conducted physiological measurements before, the significance of measurements in wound healing is established.
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Raj Mani (1999) studied this question.
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