The amino acid composition of Salmonella typhimurium LT-2 histidinol dehydrogenase is reported in detail. Several independent lines of evidence from peptide mapping, physical characterization, and end group analysis suggest that the enzyme is a dimer of two identical or very similar, indivisible, subunits, despite the existence of two complementation regions in the gene, hisD, coding for this enzyme.
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Joseph Yourno (1968) studied this question.
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