Key result
Higher HbA1c levels were positively correlated with carotid intima-media thickness (β = 0.018, P = 0.03) and plaques, though HbA1c was not a useful marker for identification (AUC 0.666).
Why the study?
Is HbA1c level associated with carotid intima-media thickness and plaques in a Chinese population without known diabetes?
Population
541 subjects without known diabetes from a Chinese population, including 67 newly diagnosed with diabetes…
Design
Cross-sectional
Authors
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HbA1c association with carotid measures should not change practice; extends links to non-diabetic Chinese adults but leaves incremental value open.
Cross-Sectional (n=541)
Is HbA1c level associated with carotid intima-media thickness and plaques in a Chinese population without known diabetes?
Effect estimate: β 0.018
p-value: p=0.03
HbA1c is linearly associated with subclinical carotid atherosclerosis in a Chinese population without known diabetes, but it is not a strong enough marker for clinical identification of atherosclerosis.
Hung et al. (2011) conducted a cross-sectional in Subclinical atherosclerosis (n=541). Haemoglobin A1c (HbA1c) levels was evaluated on Carotid intima-media thickness (IMT) (β 0.018, p=0.03). Higher HbA1c levels were positively correlated with carotid intima-media thickness (β = 0.018, P = 0.03) and plaques, though HbA1c was not a useful marker for identification (AUC 0.666).
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