Key result
EuroSCORE II demonstrated better discriminative capacity for predicting operative mortality than the original logistic EuroSCORE in high-risk octogenarian patients undergoing isolated CABG (AUC 0.772 vs 0.757).
Why the study?
Does the EuroSCORE II risk model improve the prediction of operative mortality compared to the original EuroSCORE in high-risk octogenarian patients undergoing isolated CABG?
Observational (n=105)
No
Does the EuroSCORE II risk model improve the prediction of operative mortality compared to the original EuroSCORE in high-risk octogenarian patients undergoing isolated CABG?
Effect estimate: AUC 0.772 (95% CI 0.673-0.872)
Absolute Event Rate: 0.772% vs 0.757%
p-value: p=<0.001
EuroSCORE II demonstrates better discriminative capacity than the original EuroSCORE for predicting operative mortality in high-risk octogenarian patients undergoing isolated CABG.
May enhance risk stratification in high-risk octogenarian CABG; extends prior validations but leaves open need for prospective confirmation before practice change.
INTRODUCTION: Determining operative mortality risk is mandatory for adult cardiac surgery. Patients should be informed about the operative risk before surgery. There are some risk scoring systems that compare and standardize the results of the operations. These scoring systems needed to be updated recently, which resulted in the development of EuroSCORE II. In this study, we aimed to validate EuroSCORE II by comparing it with the original EuroSCORE risk scoring system in a group of high-risk octogenarian patients who underwent coronary artery bypass grafting (CABG). MATERIAL AND METHODS: The present study included only high-risk octogenarian patients who underwent isolated coronary artery bypass grafting in our center between January 2000 and January 2010. Redo procedures and concomitant procedures were excluded. We compared observed mortality with expected mortality predicted by EuroSCORE (logistic) and EuroSCORE II scoring systems. RESULTS: We considered 105 CABG operations performed in octogenarian patients between January 2000 and January 2010. The mean age of the patients was 81.43 ± 2.21 years (80-89 years). Thirty-nine (37.1%) of them were female. The two scales showed good discriminative capacity in the global patient sample, with the AUC (area under the curve) being higher for EuroSCORE II (AUC 0.772, 95% CI: 0.673-0.872). The goodness of fit was good for both scales. CONCLUSIONS: We conclude that EuroSCORE II has better AUC (area under the ROC curve) compared to the original EuroSCORE, but both scales showed good discriminative capacity and goodness of fit in octogenarian patients undergoing isolated coronary artery bypass grafting.
No takes yet. Share an insight, caveat, or question.
Kalender et al. (2014) conducted an observational in High-risk octogenarian patients undergoing isolated CABG (n=105). EuroSCORE II vs. Original EuroSCORE was evaluated on Discriminative capacity (AUC) for operative mortality (AUC 0.772, 95% CI 0.673-0.872, p=<0.001). EuroSCORE II demonstrated better discriminative capacity for predicting operative mortality than the original logistic EuroSCORE in high-risk octogenarian patients undergoing isolated CABG (AUC 0.772 vs 0.757).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: