Key result
Routine screening for silent coronary artery disease in asymptomatic patients with type 2 diabetes is not currently recommended, as available trials have not definitively demonstrated a benefit in reducing cardiovascular outcomes.
Why the study?
Silent CAD particularly affects individuals with type 2 diabetes mellitus and poses a constant challenge regarding whether patients should be screened.
Does screening for silent coronary artery disease improve cardiovascular outcomes in asymptomatic patients with type 2 diabetes?
Does screening for silent coronary artery disease improve cardiovascular outcomes in asymptomatic patients with type 2 diabetes?
This narrative review highlights the high prevalence of silent coronary artery disease in type 2 diabetes but notes that routine screening is not currently recommended due to lack of proven outcome benefits.
Silent coronary artery disease (CAD) is one of the manifestations of heart disease that particularly affects subjects with type 2 diabetes mellitus (T2DM). From a clinical point of view, silent CAD represents a constant challenge for the diabetologist, who has to decide whether a patient could or could not be screened for this disease. In the present narrative review, several aspects of silent CAD are considered: the epidemiology of the disease, the associated risk factors, and main studies conducted, in the last 20 years, especially aimed to demonstrate the usefulness of the screening of silent CAD, to improve cardiovascular outcomes in type 2 diabetes.
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Saula Vigili de Kreutzenberg (2021) conducted a review in Silent coronary artery disease in type 2 diabetes. Screening for silent coronary artery disease vs. No routine screening was evaluated. Routine screening for silent coronary artery disease in asymptomatic patients with type 2 diabetes is not currently recommended, as available trials have not definitively demonstrated a benefit in reducing cardiovascular outcomes.
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