Key result
Young patients (≤44 years) undergoing CABG demonstrated satisfactory in-hospital and long-term adverse cardiovascular event rates comparable to older patients over a mean follow-up of 81.9 months.
Why the study?
Long-term outcomes of CABG, as well as the incidence and structure of adverse cardiovascular events according to patient age, needed analysis in young patients.
Does young age (≤44 years) compared to older age (≥45 years) affect long-term survival and adverse cardiovascular events in patients undergoing CABG?
Cohort (n=350)
Does young age (≤44 years) compared to older age (≥45 years) affect long-term survival and adverse cardiovascular events in patients undergoing CABG?
CABG provides satisfactory long-term outcomes and survival in young patients (≤44 years) that are comparable to older patients.
Comparable event rates support CABG expectations in young patients; leaves open confirmation in prospective cohorts.
OBJECTIVE: To analyze long-term outcomes of CABG in young patients, incidence and structure of adverse cardiovascular events depending on patients' age. MATERIAL AND METHODS: There were 175 young patients (up to 44 years old in accordance with WHO classification) who underwent CABG for the period from 2006 to 2016. The control group included 175 patients aged 45 years and older who were randomly selected among patients operated in the same period. Overall long-term follow-up period was 81.9±15.75 months (≈ 6.8 years). Data on long-term survival and adverse cardiovascular events were available in 86.3% of patients in general sample and 72.6% of young patients. RESULTS: Young patients undergoing CABG were usually characterized by the absence of severe concomitant diseases, moderate coronary atherosclerosis by SYNTAX Score scale, high percentage of left ventricular aneurysm and previous PCI. Incidence and structure of in-hospital and long-term adverse cardiovascular events in young and older patients confirmed satisfactory results of CABG regardless age.
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Тарасов et al. (2019) conducted a cohort in Coronary artery disease requiring CABG (n=350). Young age (≤44 years) vs. Older age (≥45 years) was evaluated on In-hospital and long-term adverse cardiovascular events. Young patients (≤44 years) undergoing CABG demonstrated satisfactory in-hospital and long-term adverse cardiovascular event rates comparable to older patients over a mean follow-up of 81.9 months.