Key result
The overall prevalence of human caliciviruses in HIV-seropositive children was 19%, with remarkable genetic diversity and no statistically significant difference in detection rates between children with and without diarrhoea (24.3% vs 16.2%, p=0.3130).
Population
105 HIV-seropositive children <14 years of age, 37 with diarrhea and 68 without diarrhea, from a children's…
Design
Cross-sectional
Authors
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Similar detection rates suggest limited diagnostic value for diarrhea in HIV-seropositive children; leaves open calicivirus pathogenicity and requires longitudinal studies.
Cross-Sectional (n=105)
No
Absolute Event Rate: 24.3% vs 16.2%
p-value: p=0.3130
Human caliciviruses, particularly diverse norovirus and sapovirus genotypes, are prevalent in HIV-seropositive children in Kenya, with similar detection rates in symptomatic and asymptomatic individuals.
Mans et al. (2013) conducted a cross-sectional in HIV infection (n=105). Human calicivirus infection was evaluated on Detection of human caliciviruses in children with diarrhoea versus without diarrhoea (p=0.3130). The overall prevalence of human caliciviruses in HIV-seropositive children was 19%, with remarkable genetic diversity and no statistically significant difference in detection rates between children with and without diarrhoea (24.3% vs 16.2%, p=0.3130).
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