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Kidney toxicity is the most common but less frequently uveitis, macular oedema, neutropenia, thrombocytopenia, nausea, fever, hair loss, and muscle pain have also been observed. 2 When administered topically or intralesionally cidofovir has not, to date, shown systemic toxicity. Surgical excision remains the best possible treatment for SCC, as it is usually curative and permits the histopathological evaluation of margins. However, the successful outcome with intralesional cidofovir in this case might be worth considering.
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H B Chittenden (2002) studied this question.
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