What question did this study set out to answer?

To construct a disease-specific growth chart for girls with Turner syndrome and evaluate its accuracy in predicting final adult stature and assessing treatment effects.

October 1, 1985Archives of Disease in ChildhoodOpen Access

Growth curve for girls with Turner syndrome.

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Authors

ALAndrew LyonJefferson Hospital MPM A PreeceUniversity of London DGDavid GrantUniversity of Hull

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Implication

Retrospective study demonstrates that standard deviation scores predict adult stature in girls with Turner syndrome, indicating oestrogen accelerates growth without altering final adult height.

Key Points

To construct a disease-specific growth chart for girls with Turner syndrome and evaluate its accuracy in predicting final adult stature and assessing treatment effects.
Compiled growth measurements from four published European cohorts to construct a standardized Turner syndrome growth chart.
Retrospectively evaluated the chart and the impact of oestrogen treatment using longitudinal height records of patients managed at a single hospital.
Height standard deviation scores derived from the disease-specific chart enabled reliable prediction of final adult stature.
Oestrogen therapy caused an initial acceleration in linear growth velocity but produced no statistically significant difference in final adult height.

Cite This Study

Lyon et al. (1985) studied this question.

synapsesocial.com/papers/6a8828cfafcf99b77fbbfd6c https://doi.org/10.1136/adc.60.10.932

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Implication

Retrospective study demonstrates that standard deviation scores predict adult stature in girls with Turner syndrome, indicating oestrogen accelerates growth without altering final adult height.

Growth curve for girls with Turner syndrome.

Discussion

Member takes

Implication

Key Points

Cite This Study

Growth curve for girls with Turner syndrome.

Discussion

Member takes

Implication

Key Points

Cite This Study

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