Between 35% and 90% of the drugs prescribed to hospitalised children are either not licensed for children's use or are prescribed outside the terms of their product licence (off label prescribing). 1 2 Subsequent adverse reactions are more likely than with licensed products (6.0% v 3.9%). 3 We analysed the extent of prescribing off labelled products in a representative cohort of children in primary care.
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Reinhild Bücheler (2002) studied this question.
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