Why the study?
Transient elastography noninvasively assesses liver stiffness, which can reflect right-sided filling pressure associated with passive liver congestion in HF patients.
Does liver stiffness measured by transient elastography predict cardiovascular death or heart failure hospitalization in ambulatory patients with chronic heart failure?
Comparison
Liver stiffness measured by transient elastography
Design
Prospective, single-center observational study
Follow-up
Mean 219 ± 86 days
Key result
Liver stiffness measured by transient elastography was independently associated with cardiovascular death or heart failure hospitalization (HR 1.05; 95% CI 1.01-1.09 per unit increment).
Authors
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May refine risk stratification in ambulatory chronic HF; hypothesis-generating and should not yet change practice.
Observational (n=85)
No
Does liver stiffness measured by transient elastography predict cardiovascular death or heart failure hospitalization in ambulatory patients with chronic heart failure?
Hazard Ratio: 1.05 (95% CI 1.01–1.09)
Liver stiffness measured by transient elastography is an independent predictor of cardiovascular death or heart failure hospitalization in ambulatory patients with chronic heart failure.
Ávila et al. (2021) conducted an observational in chronic heart failure with reduced, mid-range, and recovered left-ventricular ejection fraction (n=85). Liver stiffness measured by transient elastography was evaluated on composite of cardiovascular death or HF hospitalization (HR 1.05, 95% CI 1.01-1.09). Liver stiffness measured by transient elastography was independently associated with cardiovascular death or heart failure hospitalization (HR 1.05; 95% CI 1.01-1.09 per unit increment).
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