Key result
Mechanical tricuspid valves were associated with a significantly higher rate of the composite outcome of reintervention or heart failure readmission compared to tissue valves (40% vs. 17.3%).
Why the study?
Outcomes comparing TV reintervention or HF admission between tissue and mechanical valves after TVR needed evaluation.
Does mechanical tricuspid valve replacement compared to tissue valve replacement reduce the composite outcome of TV reintervention or HF admission in patients undergoing TVR?
Cohort (n=159)
No
Does mechanical tricuspid valve replacement compared to tissue valve replacement reduce the composite outcome of TV reintervention or HF admission in patients undergoing TVR?
In patients undergoing tricuspid valve replacement, mechanical valves were associated with a significantly higher rate of reintervention compared to tissue valves, primarily driven by valve thrombosis.
Answers are grounded in this paper and cite their sources.
May favor tissue valves for tricuspid replacement; leaves open need for randomized confirmation.
PURPOSE: We compared the composite outcome of tricuspid valve (TV) reintervention or heart failure (HF) admission in patients who underwent tricuspid valve replacement (TVR) with tissue vs. mechanical valves. PATIENTS AND METHODS: The study included 159 patients who underwent TVR from 2009 to 2019. We grouped the patients according to the valve's type into tissue valve group (n = 139) and mechanical valve group (n = 20). RESULTS: The mean age of patients was 52.4 ± 12.8 years, and 117 patients were females (73.6%). Hospital mortality occurred in 20 patients (12.6%); all of them were in the tissue valve group. The composite outcome of reintervention and HF readmission occurred in 8 patients with mechanical valves (40%) vs. 24 patients with tissue valves (17.3%), (P = 0.018). Predictors of reintervention and HF admission were female (subdistributional hazard ratio [SHR]: 1.38-34.3, P = 0.019), stroke (SHR: 1.25-8.76, P = 0.016), hypertension (SHR: 1.13-5.36, P = 0.024), and mechanical valves (SHR: 1.6-10.7, P = 0.003). In post hoc analysis, the difference in the composite outcome was derived from the difference in the reintervention rate that was higher in mechanical valves. Survival did not differ significantly between groups (P = 0.12). CONCLUSION: Mechanical TVs have a higher rate of composite outcome of reintervention or HF readmission than tissue TVs that are related mainly to higher rate of reintervention.
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Albacker et al. (2022) conducted a cohort in Tricuspid valve disease requiring replacement (n=159). Mechanical tricuspid valve vs. Tissue tricuspid valve was evaluated on Composite outcome of tricuspid valve reintervention or heart failure admission (p=0.018). Mechanical tricuspid valves were associated with a significantly higher rate of the composite outcome of reintervention or heart failure readmission compared to tissue valves (40% vs. 17.3%).
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