Radioiodine concentrations were determined in apparently normal and inflamed tissues of 12 cows after six to eight daily doses. Concentrations in diseased tissue as percentages of concentrations in corresponding normal tissue were: skin with hair, 124; macerated eyeball, 290; mammary gland, 214; and uterus, 318. Plasma thyroxine disappearance rates of four cows with injuries or infections including a bruised hock, an abscessed hock, a lacerated teat, and acute mastitis averaged 203g of normal. More rapid thyroxine disappearance rates in diseased cows could result from involvement of thyroxine in iodination reactions by phagocytosing leucocytes. Inflamed tissues also concentrate inorganic iodide.
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Miller et al. (1973) studied this question.
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