Key result
Intraoperative chlorpromazine treatment reliably prevents perioperative spasm of radial artery grafts during aortocoronary bypass grafting.
Why the study?
Does intraoperative chlorpromazine prevent radial artery graft spasm in patients undergoing aortocoronary bypass grafting?
Does intraoperative chlorpromazine prevent radial artery graft spasm in patients undergoing aortocoronary bypass grafting?
Intraoperative chlorpromazine solution is an effective method for preventing radial artery graft spasm during coronary artery bypass grafting.
A detailed description of intraoperative prevention of radial artery graft spasm using a solution of the calmodulin inhibitor chlorpromazine is presented. This method is used in direct myocardial revascularization and can reliably prevent perioperative spasm of radial artery grafts, as confirmed by intraoperative flow measurement, bypass angiography in the postoperative period, and in vitro experimental data.
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Шипулин et al. (2017) studied Radial artery spasm in aortocoronary bypass grafting. Intraoperative chlorpromazine was evaluated on Perioperative spasm of radial artery grafts. Intraoperative chlorpromazine treatment reliably prevents perioperative spasm of radial artery grafts during aortocoronary bypass grafting.
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