Why the study?
Does higher disopyramide blood level prevent neurogenic syncope during head-up tilt testing in patients with recurrent syncope?
Does higher disopyramide blood level prevent neurogenic syncope during head-up tilt testing in patients with recurrent syncope?
Higher blood levels of disopyramide are often necessary to effectively prevent neurogenic syncope during head-up tilt testing, and failure at low doses does not preclude success at higher doses.
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Higher disopyramide levels may suppress tilt-induced syncope; leaves open whether level-guided dosing improves outcomes in recurrent syncope.
Kelly et al. (1994) studied this question.
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