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May 2, 2013Cell Death and DiseaseOpen Access

Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells

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Authors

CHC-Y HuangUniversity of California, San FranciscoTLT‐C LeeLYLinda Chia‐Hui YuNational Taiwan University

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Huang et al. (2013) studied this question.

synapsesocial.com/papers/6a88417fb0d802598bf4e4adhttps://doi.org/10.1038/cddis.2013.149
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Also Consider

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  1. 1Enteral nutrients alter enterocyte function within an in vitro model similar to an acute in vivo rat model during hypoxia2002 · 5 citations
  2. 2Inhibition of Glycolysis in Cancer Cells: A Novel Strategy to Overcome Drug Resistance Associated with Mitochondrial Respiratory Defect and Hypoxia2005 · 838 citations
  3. 3Hypoxia Upregulates Activity and Expression of the Glucose Transporter GLUT1 in Alveolar Epithelial Cells1999 · 121 citations