Key result
Patients with moderate-severe mitral stenosis had significantly lower 2D global right ventricular systolic strain compared to healthy controls (-19.67 vs -24.19; P<0.001).
Why the study?
Does 2D longitudinal systolic strain and strain rate imaging detect subclinical RV systolic dysfunction in patients with moderate-severe mitral stenosis?
Case-Control (n=80)
Does 2D longitudinal systolic strain and strain rate imaging detect subclinical RV systolic dysfunction in patients with moderate-severe mitral stenosis?
Absolute Event Rate: -19.67% vs -24.19%
p-value: p=<0.001
2D RV-GLS and RV-GLSr imaging are useful for detecting subclinical right ventricular systolic dysfunction in patients with moderate-severe mitral stenosis.
Supports 2D RV strain for subclinical dysfunction detection in mitral stenosis; hypothesis-generating and requires prospective validation.
Right ventricular (RV) systolic dysfunction occurs early before clinical systemic congestion in patients with mitral stenosis (MS). Conventional echocardiographic techniques have some limitations in the assessment of RV function. To evaluate the role of two dimensional (2D) longitudinal systolic strain and strain rate imaging in detection of subclinical RV systolic dysfunction in patients with moderate-severe MS. Fifty patients with isolated MS (moderate-severe) and 30 healthy control subjects constituted the study population. Conventional echocardiography, pulsed wave tissue Doppler imaging (TDI) of the tricuspid annulus and 2D longitudinal segmental and global RV systolic strain (RV-GLS) and strain rate (RV-GLSr) measurements were obtained. Patients with MS had significantly lower RV-GLS and RV-GLSr compared to control subjects (−19.67 ± 6.23 vs. −24.19 ± 3.25, P < 0.001, and −1.49 ± 0.87 vs. −1.91 ± 0.56, P = 0.02, respectively). Patients with MS had significantly lower 2D RV-GLS and RV-GLSr compared to control group. 2D RV-GLS and RV-GLSr imaging appear to be useful in detection of subclinical RV systolic dysfunction in patients with MS.
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A 2014 study conducted a case-control in Mitral stenosis (n=80). Moderate-severe mitral stenosis vs. Healthy controls was evaluated on 2D longitudinal global right ventricular systolic strain (RV-GLS) (p=<0.001). Patients with moderate-severe mitral stenosis had significantly lower 2D global right ventricular systolic strain compared to healthy controls (-19.67 vs -24.19; P<0.001).
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