Assignment and solvent dependence of the carbon‐13 nuclear magnetic resonance spectrum of nicotine

The 13 C nmr spectrum of nicotine is assigned in Acetone‐ d 6 , DMSO‐ d 6 , Pyridine‐ d 5 , and deuterium oxide (pD 10.7, 5.4, < 1). Attention is focused on assignment of the closely‐spaced C(2) and C(6) resonances, using selective decoupling, population transfer, and long‐range coupling constant measurements. C(2) resonates at lower field in the organic solvents hut at higher field in deuterium oxide at all pD values investigated.